SPECIAL OFFER - TSO 500 - 10 Vials Only valid for 10 vials of TSO500 in one shipment 10 vials. Each vial contains approx. 500 Trichuris suis ova in 15ml of an isotonic phosphate buffered saline solution at PH 2,7 Helminths are parasitic worms.There are many different species of helminths. People acquire helminths naturally through contact with contaminated food, water or soil. Colonization is most common in children living in tropical areas with poor sanitation. To be successful, helminths must influence the immune system. People with helminths have modulated immune responses characterized by decreased production of IFNg and diminished delayed-type hypersensitivity responses. This alteration in the immune response occurs through induction of regulatory cytokines such as IL4, IL10, and TGF Helminths also alter immune responses in animal experiments showing that this is a general feature of these organisms.