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Application TSO

Instructions for Use

Please read the following instructions for use carefully. They provide important information you should know when taking TSO.

If you have questions, please consult your physician or pharmacist.

TSO

Active ingredient:

  • Trichuris suis ova

Composition:

  • 1 bottle containing the active ingredient: 500, 1000, or 2500 Trichuris suis ova.

Other ingredients:

  • 15ml phosphate buffered salt solution

Application form and Contents:

  • Original bottles with 500, 1000, and 2500 Trichuris suis ova. Supplement for treatments of immune diseases.

Examples of Application

For immune diseases such as

  • Ulcreative colitis
  • Multiple Sclerosis
  • Rheumatoid arthritis
  • Allergies
  • Allergic asthma
  • Chrohn's disease
  • Juvenile diabetes type 1
  • Lupus Erymathosis and
  • Sarcoidosis

As a supplement to conventional therapies.

Contraindications

When schould you never take TSO?

Do not take TSO if you are sensitive to the active ingredient or to any other ingredient of this medicine. TSO is also contraindicated in patients, who had their small intestines partially or completely removed. In the above mentioned doses, TSO is not suitable for children under the age of 12.

What do you need to watch during pregnancy and lacatation?

No negative influences are known at this time. In lack of appropriate clinical studies, this supplement should, however, not be taken during pregnancy.

What has to be watched when given to children?

In children under the age of 12, administration should start with an adaptation phase using very small doses, which can be increased gradually and slowly, e.g. initial administration with 1/5th of the TSO500 dosage, then 2/5, 3/5, 4/5, 5/5. Children should be only administered under a physician’s order and supervision.

Precautions for administration and warnings

Which precautions have to be observed?

Precautions or warnings are not known.

Interaction with other medications. Which other medications impact the effect of TSO and what do you have to consider, if you are taking additional other medications. No interactions with other medications are known at this point. The effect of alcohol on the central nervous system functions are not intensified or modified by TSO. If needed, TSO can be combined with all known conventional preparations, as long as they don’t have antihelmintic properties, which cancel the effect of TSO. Please also read the section “avoid when possible” below.

Which stimulants, foods, and beverages should you avoid?

TSO should not be mixed with hot or carbonated beverages.

Dosage, Method and Duration of application
The following recommendations apply as long as the physician did not issue different orders. Please comply with the application instructions, otherwise TSO may not be effective.

How much and how often should you take TSO?

With the exception for children under 12 years of age, every bottle contains a dosage, which will be taken completely every 14 days. For youth patients with moderate symptoms, the dosage TSO500 is recommended. For adult patients with moderate symptoms, the dosage TSO1000 is recommended. For elderly patients and patients with long-term illness, the dosage TSO2500 is recommended.

People who do not show a significant health improvement after the 5th dosage and who started with TSO500 or TSO1000, should switch to the next higher dose. A basic administration consists of a total of 10 oral dosages, one dosage every 14 days. In serious cases, administration with up to 20 doses may be necessary.

How should you take TSO?

You should drink the contents of one bottle completely as one dosage any time of the day, no matter if before or after a meal. After drinking one bottle, it is recommended to fill up one quarter of this bottle with a neutral liquid, sway it and then drink it, so that microorganisms which may adhere to the bottle wall, will also be ingested.

How long should you take TSO?

TSO is suitable for long term treatment.

Overdose and other application errors:
No overdoses are known at this time.

Which side effects can be associated with taking TSO?

In patients without significantly weak immune system, the rare possibility of temporary diarrhea with mild spasms exists.

Which counteractive measures need to be taken in case of side effects?

These cases require an adaptation phase, in which the dosage is cut in half until a satisfactory tolerability is achieved, and then increased again after the third dosage.

How can TSO be stopped immediately?

TSO can be stopped at any time if a conventional antihelmintic drug (e.g. mebendazole) is given.

Tips and information on shelf-life!

The expiration date of this supplement is printed on the folding box and the bottle label. Do not use supplement after this date.

How to store TSO?

Upon receipt, optimal storage is at normal refrigerator temperature between 4-8° C or 39-47°F. Do not expose supplement to excessive cold or strong heat and store out of reach of children.

  • Avoid when possible
  • Alcopar – (bephenium hydroxynaphthoate) anti-helminth
  • Anecoline – found in betel nut and used intravenously for Alzheimer’s
  • Metronidazole – (Flagyl, and others) is suspected to inhibit helminth effects
  • Anti-helminthics

Pharmaceutical Class

  • Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms
  • Diethylcarbamazine – effective against Wuchereria bancrofti, Brugia malayi, Brugia timori, tropical pulmonary eosinophilia, loiasis
  • Mebendazole – effective against pinworms, roundworms, trichuris and hookworms
  • Niclosamide – effective against tapeworms
  • Ivermectin – effective against most common intestinal worms Suramin
  • Thiabendazole – effective against roundworms, hookworms
  • Pyrantel pamoate – effective against most nematode infections
  • Paraherquamide – new anti-nematodal
  • Levamisole – very effective against hookworm
  • Piperazine and family (derivatives) – Levitra, Trazodone etc.
  • Praziquantel – effective against nematodes, some trematodes
  • Promethazine – anti-emetic
  • Triclabendazole – effective against liver flukes
  • Octadepsipeptides (eg: Emodepside) – effective against a variety of gastrointestinal helminthes
  • Amino Acetonitrile derivatives (eg: Monepantel) – effective against a variety of gastrointestinal helminths including those resistant to the other drug classes
  • Natural Class
  • Azadirachta indica (Neem) oil
  • Bitter Mellon – a noted Asian anti-helminthic.
  • Chenopodium ambrosioides – American wormseed
  • Moringa Oleifera – (Moringaceae) (Micronutrient Powder)
  • Black walnut (Juglans nigra)
  • Wormwood (Artemisia absynthium)
  • Clove (Syzygium aromaticum)
  • Tansy tea (Tanacetum vulgare)
  • Hagenia (Hagenia abyssinica)
  • Inula helenium (Elecampane) also called Horse-heal can be found in absinthe
  • Kalonji (Nigella sativa) seeds
  • Male fern (Dryopteris filix-mas)
  • Monarda – Bee balm
  • Plumeria (P. acutifolia or P. rubra) in Brazilian folk medicine.
  • Peganum harmala – is used as an anthelmintic.
  • Pumpkin seeds – and pumpkin seed oil are a traditional remedy for worms
  • Ruta graveolens – Herb-of-Grace (Common Rue)
  • Spondias mombin – java fruit

Effective date: December 2013