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Sep 13, 2024

Helminthic treatment offers a new approach to treating inflammatory bowel disease (IBD), restoring the gut microbiota and immune system balance. Studies have found that helminth colonization alters the composition and diversity of gut bacteria, increasing the beneficial ones like Clostridiales while reducing inflammatory species. Other helminths promote increased mucus production in the gut, providing a protective barrier and habitat for commensal microbes.

Benefits

If you regularly suffer from IBD, Helminthic therapy could be a promising treatment to discuss with your healthcare provider. Not only does it offer symptom relief, but it also addresses the underlying causes of IBD as a holistic approach to gut health. The microbiome-modulating effects of helminths benefit patients in several ways, including the following:

  • Increased Microbial Diversity—Helminth therapy helps restore the reduced bacterial diversity typically seen in IBD. A more varied gut microbiota can outcompete harmful bacteria, reducing the likelihood of infections and inflammation.
  • Promotion of Anti-Inflammatory Bacteria— IBD is characterized by chronic inflammation in the digestive tract. Helminths modulate this immune response, selectively encouraging the growth of beneficial bacteria with anti-inflammatory properties.
  • Improved Intestinal Barrier Function—In IBD patients, the intestinal barrier is often compromised, leading to increased gut permeability and “leaky gut” syndrome. Helminths reduce gut permeability issues by enhancing the mucus layer and tight junctions.